Lignocellulosic biomass holds immense potential as a sustainable raw material for bio-based chemicals, materials, and fuels. However, its efficient processing remains a challenge, particularly in relation to hemicelluloses (HMC), which are underutilised due to their complex composition and the resource-intensive nature of their purification. Current biorefineries focus mainly on cellulose and lignin, often discarding or inefficiently processing HMC streams. These inefficiencies lead to high costs, low yields, and increased waste. Conventional processes also rely on harsh conditions that compromise sustainability, safety, and economic viability. Efficiently valorising HMC streams is therefore crucial for achieving a more sustainable, high-performing bio-based economy in Europe.

BioSPRINT addressed these challenges by developing an intensified, integrated biorefinery approach to valorise hemicellulose streams, particularly from hardwood, straw, and industrial processes. The project applied advanced purification, catalytic conversion, and polymerisation methods to convert HMC-derived sugars into valuable bio-based resins. Innovations included membrane separation, anti-solvent precipitation, extractive-reaction techniques, and intensified catalytic and polymerisation processes. BioSPRINT embraced process intensification to reduce costs, energy use, and emissions while increasing yields and operational safety. The project demonstrated how underused HMC streams could be efficiently transformed into high-value products, aligning with circular economy goals and offering a viable alternative to fossil-based polymers.